The Clamettes were first seen working for Randy by making his fridge hats. Randy pointed out that they never stop working. Later when everyone lost their hair because of him, he got attacked by the Clamettes, who also seemed to have lost hair because of Randy's hat ("Milo's Big Idea").
The Clamettes were then seen in Clamanda's cheer squad at the "All-Species High School Cheering Squad." They remained silent when Clamanda was taunting or fighting Clamantha, but they still have some sort of grudge on Clamantha. After the Clamettes did their cheer, Coach Salmons first said that the winners were the Clamettes. However, he then announced that the real winners were Clamantha's cheer squad, having a bigger trophy than the Clamettes. The Clamettes carried Clamanda away when she started plotting revenge on Clamantha ("We've Got Fish Spirit").